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No 2 / 4

DNA-adducts in fish liver as biomarkers for monitoring of the aquatic environment (DNA-addukter)

Date: 1.1.1995-31.12.1998
Code: 6614
Department: Åbo Akademi University / Faculty of Mathematics and Natural Sciences (MNF), The Institute of Parasitology
Address: BioCity, Artillerigatan 6, FIN-20520 Åbo
Phone +358-2-2154 301
Fax +358-2-2154 748
E-mail gbylund@abo.fi
Project leader: FD Göran Bylund, Föreståndare, forskare (1.1.1995-)
Researchers: FK Chira Malmström (1.1.1995-)
Type of research: 0 (0=Within duty, 1=Ordered research, 2=Co-operation)
- basic research 80 %
- applied research 20 %
Finnish funding organizations: Tor och Maj Nesslings fond () FIM
Man months: Totally: 48 months
Partners: NOOA, Environm.Conserv.Division, Seattle, USA Inst.Exp.& Clin.Medicine, Tallin, Estonia
Contacts: Projektet är en del av ett större forskningsprogram: fisksjukdomar som indikatorer på vattenkvalitet
Keywords: forskningsmetoder, djursjukdomar: fisk, symptom, tutkimusmenetelmät, eläintaudit: kalat, oireet, DNA-adducter, flundra, genotoxicitet, PAH-föreningar, DNA-adducts, flounder, genotoxicity, PAH-compounds,

Although we know that foreign chemicals in the aquatic environment influence on fish health parameters, it has so far been difficult to establish cause/effects-relationships, to relate disease symptoms in fish to specific pollutants and chemicals etc.The aim of the project is to develope methods and obtain results based on which we will be able to: test and monitor the aquatic environment concerning genotoxic compounds; through exposure experiments test the genotoxic effects of specific chemicals or complex compounds occuring in effluents from industries, cities etc.; test for and define the biological effects in s.c."hot spots" like recipient areas, dumping areas etc.; utilize certain macroscopical symptoms on fish liver for evaluating the biological quality of a water area

Publication(s)

15.2.1996 / 19.2.1996