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No 3 / 4

Immunomodulation in rainbow trout (Fiskimmunologi)

Date: 1.1.1995-31.12.1998
Code: 6613
Department: Åbo Akademi University / Faculty of Mathematics and Natural Sciences (MNF), The Institute of Parasitology
Address: BioCity, Artillerigatan 6, FIN-20520 Åbo
Phone +358-2-2154 301
Fax +358-2-2154 748
E-mail gbylund@abo.fi
Project leader: FD Göran Bylund, Föreståndare, forskare (1.1.1995-)
Researchers: FK Tuula Lunden (1.1.1995-)
Type of research: 0 (0=Within duty, 1=Ordered research, 2=Co-operation)
- basic research 80 %
- applied research 20 %
Man months: Totally: 48 months
Partners: Biokemian laitos, Turun yliopisto, Finland
Contacts: Arbetet ansluter sig nära till andra arbeten inom immunoprofylax och immunotoxikologi
Keywords: immunitet, fisk, kemiska föreningar, antibiotika, immuniteetti, kala, kemialliset yhdisteet, antibiootit, immunomodulatorer, immunoprofylaxi, glukaner, selen, immunomodulators, immunoprophylactic, glucans, selenium, immunotoxicology,

Principally the immune mechanisms in fish are similar to those of higher vertebrates.The most important cellular components, signal substances etc. are similar to those in higher animals.In fish, however, the system is more primitive, the functions are slower and "less effective".We know that some chemicals have stimulating effect on the immune functions in fish, other have an immunosupressive effect.In the project works we try to clarify the effects and mechanisms in fish of some compounds (glucans, selenium etc.) with well known immunostimulative effects in higher animals.Moreover we try to evaluate the immunomodulartory effects of antimicrobial drugs used in fish farming.Our aim is to obtain results and data based on which we can work out effective immunoprophylactic programs for the fish farming industry and with application also in immunotoxicology.

Publication(s)

15.2.1996 / 19.2.1996